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Alternate Names: Sentry Simethicone, Mylanta Gas Relief, Gas-X, Infacol
CAS No: 8050-81-5
Mol Formula: C6H18O4Si3
Mol Weight: 238.46 g/mol
IUPAC Name: dioxosilane;methoxy-dimethyl-trimethylsilyloxysilane
API Description: Simethicone is a silicon based surfactant that decreases the surface tension of gastrointestinal gas bubbles to facilitate their elimination. It has a favourable safety profile as it is not systemically absorbed. Simethicone has been in use since the 1940s but was granted FDA approval in 1952. Simethicone is a mixture of polydimethylsiloxanes with antifoaming and anti-bloating effects. Simethicone reduces the surface tension of gas bubbles causing them to coalesce into larger bubbles that can be passed more easily by belching or flatulence.