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Alternate Names: (1S,3S,5S)-2-((2S)-2-Amino-2-(3-hydroxyadamantan-1-yl)acetyl)-2-azabicyclo[3.1.0]hexane-3-carbonitrile hydrochloride dihydrate
CAS No: 1073057-20-1
PubChem CID: 91617922
Mol Formula: C18H30ClN3O4
Mol Weight: 387.9 g/mol
IUPAC Name: (1S,3S,5S)-2-[(2S)-2-amino-2-(3-hydroxy-1-adamantyl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile;dihydrate;hydrochloride
Drug Class: DPP-4 inhibitors, Hypoglycemics
Commercial / Development Status: Commercial APIs
Source / Manufacturing Origin: Synthetic APIs
API Description: Saxagliptin hydrochloride dihydrate is a crystalline form of saxagliptin, an oral hypoglycemic drug used for the treatment of type 2 diabetes mellitus. It belongs to the class of dipeptidyl peptidase-4 (DPP-4) inhibitors. Saxagliptin works by increasing the levels of incretin hormones such as GLP-1 and GIP, which in turn increase insulin release from pancreatic beta cells in a glucose-dependent manner and reduce glucagon secretion from pancreatic alpha cells. This leads to reduced fasting and postprandial blood glucose levels.
