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Sodium Phenylbutyrate API Suppliers - Manufacturers and Distributors

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Sodium Phenylbutyrate

Alternate Names: Buphenyl, TriButyrate, Ammonaps, Pheburane

CAS No: 1716-12-7

PubChem CID: 5258

Mol Formula: C10H11NaO2

Mol Weight: 186.18 g/mol

IUPAC Name: sodium;4-phenylbutanoate

API Description: Sodium phenylbutyrate is the organic sodium salt of 4-phenylbutyric acid. A prodrug for phenylacetate, it is used to treat urea cycle disorders. It has a role as a prodrug, an EC 3.5.1.98 (histone deacetylase) inhibitor, a neuroprotective agent, an orphan drug and a geroprotector. It contains a 4-phenylbutyrate. Sodium Phenylbutyrate is the sodium salt of phenylbutyrate, a derivative of the short-chain fatty acid butyrate, with potential antineoplastic activity. Phenylbutyrate reversibly inhibits class I and II histone deacetylases (HDACs), which may result in a global increase in gene expression, decreased cellular proliferation, increased cell differentiation, and the induction of apoptosis in susceptible tumor cell populations.

                   
Sodium Phenylbutyrate

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