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Alternate Names: Sodium nafcillin, Nafcillin sodium anhydrous, Nallpen
CAS No: 985-16-0
PubChem CID: 23667630
Mol Formula: C21H21N2NaO5S
Mol Weight: 436.5 g/mol
IUPAC Name: sodium;(2S,5R,6R)-6-[(2-ethoxynaphthalene-1-carbonyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
API Description: Nafcillin Sodium Anhydrous is the anhydrous form of the sodium salt of nafcillin, a narrow-spectrum beta-lactamase-resistant penicillin with antibacterial activity. Nafcillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis.
