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Alternate Names: Pyrukynd, Mitapivat hemisulfate sesquihydrate [WHO-DD], AG-348 Hemisulfate Sesquihydrate
CAS No: 2151847-10-6
PubChem CID: 134693700
Mol Formula: C48H60N8O13S3
Mol Weight: 1053.2 g/mol
IUPAC Name: N-[4-[4-(cyclopropylmethyl)piperazine-1-carbonyl]phenyl]quinoline-8-sulfonamide;sulfuric acid;trihydrate
API Description: Mitapivat Sulfate is used to treat pyruvate kinase deficiency (PKD), a rare genetic disorder that causes chronic hemolytic anemia. It works by activating the pyruvate kinase enzyme in red blood cells, improving their energy production and lifespan. Mitapivat is also being studied for use in thalassemia and sickle cell disease.
