Find verified Metformin Hydrochloride API manufacturers, suppliers, and distributors across the globe. Explore companies that offer high-purity Metformin Hydrochloride for pharmaceutical use, along with product details, certifications, and reliable sourcing options. Compare prices, check availability, and connect directly with trusted suppliers for Metformin Hydrochloride API.
Alternate Names: Metformin, Metformin HCl, 1,1-Dimethylbiguanide hydrochloride
CAS No: 1115-70-4
Mol Formula: C4H12ClN5
Mol Weight: 165.62 g/mol
IUPAC Name: 3-(diaminomethylidene)-1,1-dimethylguanidine;hydrochloride
API Description: Metformin is the most popular anti-diabetic drug in the United States and one of the most prescribed drugs in the country overall, with nearly 35 million prescriptions filled in 2006 for generic metformin alone. Metformin is a biguanide antihyperglycemic agent used for treating non-insulin-dependent diabetes mellitus (NIDDM). It improves glycemic control by decreasing hepatic glucose production, decreasing glucose absorption and increasing insulin-mediated glucose uptake. Metformin is the only oral antihyperglycemic agent that is not associated with weight gain. Metformin may induce weight loss and is the drug of choice for obese NIDDM patients. When used alone, metformin does not cause hypoglycemia; however, it may potentiate the hypoglycemic effects of sulfonylureas and insulin. Its main side effects are dyspepsia, nausea and diarrhea. Dose titration and/or use of smaller divided doses may decrease side effects. Metformin should be avoided in those with severely compromised renal function (creatinine clearance < 30 ml/min), acute/decompensated heart failure, severe liver disease and for 48 hours after the use of iodinated contrast dyes due to the risk of lactic acidosis. Lower doses should be used in the elderly and those with decreased renal function. Metformin decreases fasting plasma glucose, postprandial blood glucose and glycosolated hemoglobin (HbA1c) levels, which are reflective of the last 8-10 weeks of glucose control. Metformin may also have a positive effect on lipid levels. In 2012, a combination tablet of linagliptin plus metformin hydrochloride was marketed under the name Jentadueto for use in patients when treatment with both linagliptin and metformin is appropriate.
Apitoria Pharma Private Limited is a wholly owned subsidiary of Aurobindo Pharma Limited, established in 2023. It specializes in the manufacturing of Active Pharmaceutical Ingredients (APIs) and operates with a focus on agility, reliability, and innovation. The company offers a d verse portfolio of over 250 API molecules, including antibiotics, CNS & CVS drugs, antidiabetics, oncology products, and complex molecules. - Show More
Lupin Limited is a leading Indian multinational pharmaceutical company headquartered in Mumbai. Founded in 1968 by Dr. Desh Bandhu Gupta, Lupin has grown to become the 7th largest pharmaceutical company in India and one of the top 10 generic pharmaceutical companies globally by r venue. - Show More
Aarti Drugs Ltd (ADL) is a leading Indian pharmaceutical company established in 1984 and is part of the $6 billion Aarti Group of Industries. The company specializes in the manufacturing of Active Pharmaceutical Ingredients (APIs), pharma intermediates, specialty chemicals, and f rmulations, with a strong domestic and international presence. - Show More
With over 85 years of experience, Uquifa provides comprehensive services supporting projects from proof of concept to commercial manufacturing. Uquifa’s business model is built on a quality manufacturing platform and a strong track record of service and reliability. Uquifa Grou manufactures Active Pharmaceutical Ingredients (APIs) and intermediates for the global pharmaceutical and animal health industries. - Show More
Macleods Pharmaceuticals Ltd. is a privately held, vertically integrated global pharmaceutical company headquartered in Mumbai, Maharashtra, India. Established in 1989, the company develops, manufactures, and markets a wide range of pharmaceutical formulations across major therap utic areas, including anti-infectives, cardiovascular, anti-diabetic, dermatology, and hormone treatments. - Show More
USV Private Limited is a prominent Indian multinational pharmaceutical and biotechnology company headquartered in Mumbai, Maharashtra. Established in 1961 by Vithal Balkrishna Gandhi, USV began as a joint venture with USV&P Inc., a subsidiary of Revlon, USA. Today, it operates in over 75 countries and is recognized as a leader in the production of Metformin in India. - Show More
Shandong Luwei Pharmaceutical Co., Ltd. was established in January 2007 with the registered capital of $ 8 million and more than 2,000 staffs at present. It is located in Shuangfeng Industrial Park in Zichuan, covers 200 acres, produces vitamin C (API) 30,000 tons per year, and i one of the top five vitamin C producers in the whole nation and the only vitamin C producer in Shandong Province. - Show More
Olon S.p.A. is an Italian multinational company specializing in the development and production of active pharmaceutical ingredients (APIs) for the pharmaceutical industry. Headquartered in Rodano, near Milan, Italy, Olon has established itself as a significant player in the globa API market. - Show More
Our group brings you Sohan Healthcare Pvt Ltd. For more than three decades, our group has serviced the Indian market, upholding significant values of supremacy complimented with authenticity. Be it Diabetes drugs, edible oil, fertilizers, agricultural machinery treading or road c nstruction; our work towards creating a better future has been applauded and valued. It is this relentless perseverance for taking our products like ...Our group brings you Sohan Healthcare Pvt Ltd. For more than three decades, our group has serviced the Indian market, upholding significant values of supremacy complimented with authenticity. Be it Diabetes drugs, edible oil, fertilizers, agricultural machinery treading or road construction; our work towards creating a better future has been applauded and valued. It is this relentless perseverance for taking our products like Diabetes medicines and services to new heights, that led us to. Our primary focus, based on extensive market research, is on manufacturing anti-diabetes medicines. Diabetes drug manufacturing is estimated to be one of the fastest growing therapeutic segments. Our dedicated team is currently working on lining up a battery of medication other than diabetic medicines that we will soon be able to manufacture. Our manufacturing, R&D, distribution and other facilities are maintained to meet the present market needs & future challenges so that our drugs for diabetes are of best quality. We are known for our product quality, business commitment, global reach and for our ability to serve our customers as per their requirement. - Show More
With more than 50 years history in pharmaceutical industry, Beijing Pharmaceutical CO.,LTD (BPC), a member of IFPW (International Federation of Pharmaceutical Wholesalers), is a large state-owned holding pharmaceutical enterprise, a nation’s leading pharmaceutical wholesaler, d stributer, manufacturer and retail chain owner, with total assets RMB 3.1 billion, and annual sales RMB 8 billion. BPC comprises 6 branch companies ...With more than 50 years history in pharmaceutical industry, Beijing Pharmaceutical CO.,LTD (BPC), a member of IFPW (International Federation of Pharmaceutical Wholesalers), is a large state-owned holding pharmaceutical enterprise, a nation’s leading pharmaceutical wholesaler, distributer, manufacturer and retail chain owner, with total assets RMB 3.1 billion, and annual sales RMB 8 billion. BPC comprises 6 branch companies and 7 holding subsidiaries, operating more than 20,000 SKUs which cover Chemical Medicines, Traditional Chinese Medicines, Bio and blood products, herbal pieces, Medical instruments, Active pharmaceutical ingredients and Healthcare products, more than 5,000 of which are operated as exclusive agency. Its operation scales ranks first in Beijing and top ten among the largest pharmaceutical wholesalers in China. BPC is one of the first pharmaceutical distribution and manufacturing companies that pass the national GSP and GMP authentication. In addition, it is qualified to export and import various kinds of medicine and medical equipment, and it is a qualified third-party logistics as well. BPC’s Beijing-based business network covers more than 20 provinces and cities in China, serving the market in five major segements which include hospitals, community clinics, commercial distribution, retail chain, manufacture &OEM. The BPC’s over 14,000 customers comprise Hospitals, Community clinics, Commercial distributors and Retail drugstores. BPC’s self-owned branded retail chain has over 1300 retail drug stores in Beijing, Shandong and Liaoning. BPC establish China’s first pharmaceutical logistics center with auto picking system. Since it leverages IT through out the whole company, enable BPC to deliver various effective and high quiality services to its customers. In addition, BPC’s prfessional and powerful sales force extend BPC’s bussiness to a broader range of areas. BPC is an advocator of business philosophy, always sticking “quality is first”. In addition, BPC is not only focuses on its business development, but also actively takes social responsibility, endeavor in delivering the best products and services to its customers through persistent exploration and innovation. With the issue of the new Healthcare Reform policy, BPC will not just satisfied with what it has had, but dedicated to contribute more to the nation, and even worldwide healthcare industry. - Show More
