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Alternate Names: Lapatinib ditoluenesulfonate monohydrate, Tyverb, Tycerb
CAS No: 388082-78-8
PubChem CID: 11557040
Mol Formula: C43H44ClFN4O11S3
Mol Weight: 943.5 g/mol
IUPAC Name: https://pubchem.ncbi.nlm.nih.gov/image/imgsrv.fcgi?cid=11557040&t=l
API Description: Lapatinib Ditosylate is the ditosylate salt of lapatinib, a synthetic, orally-active quinazoline with potential antineoplastic activity. Lapatinib reversibly blocks phosphorylation of the epidermal growth factor receptor (EGFR), ErbB2, and the Erk-1 and-2 and AKT kinases; it also inhibits cyclin D protein levels in human tumor cell lines and xenografts. EGFR and ErbB2 have been implicated in the growth of various tumor types.
