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Alternate Names: Tasmar, Tolcapona, Tolcaponum, Ro 407592
CAS No: 134308-13-7
PubChem CID: 4659569
Mol Formula: C14H11NO5
Mol Weight: 273.24 g/mol
IUPAC Name: (3,4-dihydroxy-5-nitrophenyl)-(4-methylphenyl)methanone
API Description: Tolcapone is a drug that inhibits the enzyme catechol-O-methyl transferase (COMT). It is used in the treatment of Parkinson's disease as an adjunct to levodopa/carbidopa medication. It is a yellow, odorless, non-hygroscopic, crystalline compound. Tolcapone is associated with a risk of hepatotoxicity. Tolcapone is a Catechol-O-Methyltransferase Inhibitor. The mechanism of action of tolcapone is as a Catechol O-Methyltransferase Inhibitor.