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Alternate Names: Thiola, Mucolysin, Capen, Epatiol, Thiosol
CAS No: 1953-02-2
PubChem CID: 5483
Mol Formula: C5H9NO3S
Mol Weight: 163.20 g/mol
IUPAC Name: 2-(2-sulfanylpropanoylamino)acetic acid
API Description: Tiopronin is a prescription thiol drug used primarily in the treatment of severe homozygous cystinuria. Patients with cystinuria excrete high levels of cystine in their urine and are at risk for kidney stone formation. Tiopronin is used as a second-line therapy to control the rate of cystine precipitation and excretion, and prevent kidney stone formation. It is used after a failure of the non-pharmacological first line treatment consisting of increased fluid intake, restriction of sodium and protein, and urinary alkalinization.