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Alternate Names: RGH-896, (1-Piperidineacetamide, N-(2,3-dihydro-2-oxo-6-benzoxazolyl)-4-[(4-fluorophenyl)methyl]-alpha-oxo-)
CAS No: 496054-87-6
PubChem CID: 10200813
Mol Formula: C21H20FN3O4
Mol Weight: 397.4 g/mol
IUPAC Name: 2-[4-[(4-fluorophenyl)methyl]piperidin-1-yl]-2-oxo-N-(2-oxo-3H-1,3-benzoxazol-6-yl)acetamide
API Description: Radiprodil is an investigational drug with demonstrated potential for treating seizures associated with GRIN-related neurodevelopmental disorders, a condition caused by gain-of-function mutations in the GRIN2B gene. Clinical trials have shown that radiprodil is well-tolerated and significantly reduces seizure frequency in affected individuals. It is a selective, potent negative allosteric modulator of the NR2B subunit of the NMDA receptor, which helps to control overactive brain activity characteristic of these disorders.
