Find verified Krm-II-81 API manufacturers, suppliers, and distributors across the globe. Explore companies that offer high-purity Krm-II-81 for pharmaceutical use, along with product details, certifications, and reliable sourcing options. Compare prices, check availability, and connect directly with trusted suppliers for Krm-II-81 API.
Alternate Names: 5-(8-ethynyl-6-pyridin-2-yl-4H-imidazo[1,5-a][1,4]benzodiazepin-3-yl)-1,3-oxazole
CAS No: 2014348-91-3
PubChem CID: 122582003
Mol Formula: C21H13N5O
Mol Weight: 351.4 g/mol
IUPAC Name: 5-(8-ethynyl-6-pyridin-2-yl-4H-imidazo[1,5-a][1,4]benzodiazepin-3-yl)-1,3-oxazole
API Description: KRM-II-81 is a GABAA receptor potentiator, specifically an imidazodiazepine, being developed as a novel treatment for neurological and psychiatric disorders. It is being investigated for its potential in treating epilepsy, pain, and anxiety due to its ability to enhance the effects of GABA, a neurotransmitter that inhibits nerve activity. KRM-II-81 is showing promise in preclinical studies, particularly for pharmacoresistant epilepsy, and is also being explored for its potential in managing pain and anxiety.
