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Alternate Names: KW-6002, nouriast, Nourianz, KW 6002
CAS No: 155270-99-8
PubChem CID: 5311037
Mol Formula: C20H24N4O4
Mol Weight: 384.4 g/mol
IUPAC Name: 8-[(E)-2-(3,4-dimethoxyphenyl)ethenyl]-1,3-diethyl-7-methylpurine-2,6-dione
API Description: Istradefylline is an adenosine receptor antagonist that is used as adjunctive therapy to levodopa/carbidopa in patients with Parkinson disease experiencing difficulty with “off” episodes when motor symptoms breakthrough on treatment. Istradefylline has been associated with a low rate of serum enzyme elevations during therapy, but has not been linked to cases of clinically apparent liver injury with jaundice.
