trans-2,2-Dimethyl-3-phenyl-4-(p-hydroxyphenyl)-7-methoxy chroman (CAS No: 57897-46-8) is a key pharmaceutical intermediate used in the synthesis of APIs Ormeloxifene hydrochloride. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: rel-4-((3R,4R)-7-Methoxy-2,2-dimethyl-3-phenylchroman-4-yl)phenol, 4-((3R,4R)-7-Methoxy-2,2-dimethyl-3-phenylchroman-4-yl)phenol
CAS No: 57897-46-8
PubChem CID: 12274746
Mol Formula: C24H24O3
Mol Weight: 360.4 g/mol
Used in API: Ormeloxifene hydrochloride
IUPAC Name: 4-[(3R,4R)-7-methoxy-2,2-dimethyl-3-phenyl-3,4-dihydrochromen-4-yl]phenol
API Intermediate Description: Trans-2,2-Dimethyl-3-phenyl-4-(p-hydroxyphenyl)-7-methoxy chroman is primarily used as a key intermediate in synthesizing powerful non-steroidal anti-fertility drugs (contraceptives), acting as a precursor to compounds like Ormeloxifene (Centchroman) and related selective estrogen receptor modulators (SERMs) for treating hormone-related issues like osteoporosis and potentially breast cancer, leveraging its estrogenic/antiestrogenic properties to disrupt reproductive cycles.
