Tert-butyl2-(11-oxo-6,11-dihydrodibenzo[b,e]oxepin-2-yl)acetate (CAS No: 1018464-42-0) is a key pharmaceutical intermediate used in the synthesis of APIs Olopatadine. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: SCHEMBL31003294
CAS No: 1018464-42-0
PubChem CID: 23323862
Mol Formula: C20H20O4
Mol Weight: 324.4 g/mol
Used in API: Olopatadine
IUPAC Name: tert-butyl 2-(11-oxo-6H-benzo[c][1]benzoxepin-2-yl)acetate
API Intermediate Description: Tert-butyl2-(11-oxo-6,11-dihydrodibenzo[b, e]oxepin-2-yl)acetate serves as a protected intermediate, specifically a protected form of the key precursor acid (Isoxepac), in synthesizing Olopatadine; it's used in Wittig reactions with 3-dimethylaminopropyltriphenylphosphonium salts, followed by deprotection (like hydrolyzing the tert-butyl ester), to form the characteristic double bond and yield Olopatadine.
![Tert-butyl2-(11-oxo-6,11-dihydrodibenzo[b,e]oxepin-2-yl)acetate](https://pubchem.ncbi.nlm.nih.gov/image/imgsrv.fcgi?cid=23323862&t=l)
