tert-Butyl 4-(6-(6-bromo-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydro-pyrido(2,3-d)pyrimidin-2-ylamino)-pyridin-3-yl)-piperazine-1-carboxylate (CAS No: 571188-82-4) is a key pharmaceutical intermediate used in the synthesis of APIs Palbociclib. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: 6-Bromo-8-cyclopentyl-2-[[5-(4-Boc-1-piperazinyl)-2-pyridyl]amino]-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one, t-butyl 4-(6-((6-bromo-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate
CAS No: 571188-82-4
PubChem CID: 11157536
Mol Formula: C27H34BrN7O3
Mol Weight: 584.5 g/mol
Used in API: Palbociclib
IUPAC Name: tert-butyl 4-[6-[(6-bromo-8-cyclopentyl-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]piperazine-1-carboxylate
API Intermediate Description: Tert-butyl 4-(6-(6-bromo-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydro-pyrido[3-d]pyrimidin-2-ylamino)-pyridin-3-yl)-piperazine-1-carboxylate is a crucial intermediate in the synthesis of Palbociclib, a selective CDK4/6 inhibitor used for breast cancer treatment. It serves as a precursor for introducing the 6-acetyl group in the final API.
