(S)-2-((4-(Trifluoromethyl)phenoxy)methyl)oxirane (CAS No: 256372-58-4) is a key pharmaceutical intermediate used in the synthesis of APIs Seladelpar. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: (2S)-2-{[4-(trifluoromethyl)phenoxy]methyl}oxirane, Oxirane, [[4-(trifluoromethyl)phenoxy]methyl]-, (2S)-
CAS No: 256372-58-4
PubChem CID: 33786616
Mol Formula: C10H9F3O2
Mol Weight: 218.17 g/mol
Used in API: Seladelpar
IUPAC Name: (2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]oxirane
API Intermediate Description: (S)-2-((4-(Trifluoromethyl)phenoxy)methyl)oxirane serves as a key chiral building block or intermediate in the synthesis of Seladelpar (Livdelzi), the drug used for Primary Biliary Cholangitis (PBC). This specific epoxide structure provides the crucial stereochemistry needed for Seladelpar's therapeutic activity as a selective PPAR-delta agonist, helping form its complex structure and influencing its interaction with biological targets, ultimately reducing liver inflammation and itching in PBC patients.
