Pemetrexed acid (CAS No: 137281-39-1) is a key pharmaceutical intermediate used in the synthesis of APIs Pemetrexed disodium. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: 4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic Acid, Pemetrexed Impurity 7
CAS No: 137281-39-1
PubChem CID: 135405776
Mol Formula: C15H14N4O3
Mol Weight: 298.30 g/mol
Used in API: Pemetrexed disodium
IUPAC Name: 4-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic acid
API Intermediate Description: Pemetrexed acid is the free acid form of pemetrexed, a folate analog and antifolate chemotherapeutic agent. It inhibits several folate-dependent enzymes involved in nucleotide synthesis, thereby interfering with DNA and RNA production in rapidly dividing cancer cells.
