ethyl 5-amino-1-(2-fluorobenzyl)-1H-pyrazole-3-carboxylate (CAS No: 256504-39-9) is a key pharmaceutical intermediate used in the synthesis of APIs Riociguat. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: 5-Amino-1-(2-fluoro-benzyl)-1H-pyrazole-3-carboxylic acid ethyl ester , 1H-Pyrazole-3-carboxylic acid, 5-amino-1-[(2-fluorophenyl)methyl]-, ethyl ester
CAS No: 256504-39-9
PubChem CID: 11391384
Mol Formula: C13H14FN3O2
Mol Weight: 263.27 g/mol
Used in API: Riociguat
IUPAC Name: ethyl 5-amino-1-[(2-fluorophenyl)methyl]pyrazole-3-carboxylate
API Intermediate Description: Ethyl 5-amino-1-(2-fluorobenzyl)-1H-pyrazole-3-carboxylate is a substituted pyrazole derivative featuring both amino and ester functional groups. It serves as a versatile intermediate in medicinal chemistry, allowing further functionalization at the pyrazole core. The presence of a fluorobenzyl substituent enhances its relevance in drug discovery and structure–activity relationship studies.