Dimethyl (3-oxo-1,3-dihydro-2-benzofuran-1-yl)phosphonate (CAS No: 61260-15-9) is a key pharmaceutical intermediate used in the synthesis of APIs Olaparib. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: 3-dimethoxyphosphoryl-3H-isobenzofuran-1-one, 3-oxo-1,3-dihydroisobenzofuran-1-ylphosphonic acid
CAS No: 61260-15-9
PubChem CID: 11118213
Mol Formula: C10H11O5P
Mol Weight: 242.16 g/mol
Used in API: Olaparib
IUPAC Name: 3-dimethoxyphosphoryl-3H-2-benzofuran-1-one
API Intermediate Description: Dimethyl (3-oxo-1,3-dihydro-2-benzofuran-1-yl)phosphonate, often referred to as (3-oxo-1,3-dihydroisobenzofuran-1-yl) dimethyl phosphate, serves as a crucial intermediate in the synthesis of Olaparib, acting as a key building block that forms part of the core phthalazinone structure by reacting with precursors like 2-fluoro-5-formylbenzoic acid to eventually incorporate the naphthyridine ring system, enabling the creation of this vital PARP inhibitor anticancer drug.
