5,6-Diphenylpyrazin-2-ol (CAS No: 18591-57-6) is a key pharmaceutical intermediate used in the synthesis of APIs Selexipag. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: 5,6-Diphenylpyrazinol, 5,6-diphenyl-1H-pyrazin-2-one
CAS No: 18591-57-6
PubChem CID: 619180
Mol Formula: C16H12N2O
Mol Weight: 248.28 g/mol
Used in API: Selexipag
IUPAC Name: 5,6-diphenyl-1H-pyrazin-2-one
API Intermediate Description: 5,6-Diphenylpyrazin-2-ol is a crucial intermediate and potential impurity in the synthesis of Selexipag (Uptravi), a medication for pulmonary arterial hypertension (PAH) that acts as a prostacyclin receptor agonist, with its core structure providing the diphenylpyrazine part of the final Selexipag molecule. It serves as a building block, often reacting to form the more complex N-isopropylamino-butoxy side chain that defines Selexipag's therapeutic activity, and its presence as a related compound is monitored during manufacturing.
