5-Amino-2,4-di-tert-butylphenol (CAS No: 873055-58-4) is a key pharmaceutical intermediate used in the synthesis of APIs Ivacaftor. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: Ivacaftor Impurity 10, Phenol, 5-amino-2,4-bis(1,1-dimethylethyl)-
CAS No: 873055-58-4
PubChem CID: 44176226
Mol Formula: C14H23NO
Mol Weight: 221.34 g/mol
Used in API: Ivacaftor
IUPAC Name: 5-amino-2,4-ditert-butylphenol
API Intermediate Description: 5-Amino-2,4-di-tert-butylphenol (5-A-DTBP) is primarily a crucial pharmaceutical intermediate, most notably used in synthesizing Ivacaftor, a drug for cystic fibrosis, by reacting with oxo-dihydroquinoline carboxylic acid. It also serves as a building block in organic synthesis, finds application in analytical chemistry (as a standard for HPLC), and is studied for potential roles in creating other antioxidants and specialty chemicals, though its key role remains within pharmaceutical manufacturing.
