4-Fluoro-2-methyl-1-(1-methylethyl)-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzimidazole (CAS No: 1231930-37-2) is a key pharmaceutical intermediate used in the synthesis of APIs Abemaciclib. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: 4-Fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole-6-boronic acid pinacol ester, 4-Fluoro-1-isopropyl-2-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzimidazole
CAS No: 1231930-37-2
PubChem CID: 67434758
Mol Formula: C17H24BFN2O2
Mol Weight: 318.2 g/mol
Used in API: Abemaciclib
IUPAC Name: 4-fluoro-2-methyl-1-propan-2-yl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzimidazole
API Intermediate Description: 4-fluoro-1-isopropyl-2-methyl-6-(4,4,5,5-tetramethyl- 1,3,2- dioxaborolan-2-yl)-1H-benzo[d] imidazole is used as a pharmaceutical intermediate in the synthesis of more complex molecules, particularly in the development of active pharmaceutical ingredients (APIs). It is a building block used in organic chemistry to create new compounds, likely for drug discovery and research, as it contains a boronic ester functional group that is useful in cross-coupling reactions.