4-chloro-6,7-dimethoxyquinoline (CAS No: 35654-56-9) is a key pharmaceutical intermediate used in the synthesis of APIs Cabozantinib and Tivozanib. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: 6,7-Dimethoxy-4-chloroquinoline, QUINOLINE, 4-CHLORO-6,7-DIMETHOXY-
CAS No: 35654-56-9
PubChem CID: 459610
Mol Formula: C11H10ClNO2
Mol Weight: 223.65 g/mol
Used in APIs: Cabozantinib and Tivozanib
IUPAC Name: 4-chloro-6,7-dimethoxyquinoline
API Intermediate Description: 4-Chloro-6,7-dimethoxyquinoline is a vital chemical building block, primarily used as a key intermediate in synthesizing advanced pharmaceuticals, especially targeted cancer drugs like Cabozantinib (Cometriq/Cabometyx) and Tivozanib (Fotivda), which are tyrosine kinase inhibitors for treating cancers like kidney and thyroid cancer. Beyond cancer, it's explored for antimicrobial development and as a research tool to study kinase inhibitors and create novel biologically active quinoline derivatives for various therapeutic areas.
