3-Cyanomethyleneazetidinium chloride (CAS No: 1314910-43-4) is a key pharmaceutical intermediate used in the synthesis of APIs Baricitinib. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: Azetidinium, 3-(cyanomethylene)-, chloride, Baricitinib Impurity 19
CAS No: 1314910-43-4
PubChem CID: 55300440
Mol Formula: C5H7ClN2
Mol Weight: 130.57 g/mol
Used in API: Baricitinib
IUPAC Name: 2-(azetidin-3-ylidene)acetonitrile;hydrochloride
API Intermediate Description: 3-Cyanomethyleneazetidinium chloride is a quaternary ammonium salt featuring a strained azetidinium ring (a four-membered nitrogen-containing ring) with a cyanomethylene substituent. It serves as a highly reactive intermediate in the synthesis of β-lactam antibiotics and related heterocyclic compounds due to its electrophilic nature and ring strain.