2(1H)-Pyrimidinone, hydrochloride (1:1) (CAS No: 38353-09-2) is a key pharmaceutical intermediate used in the synthesis of APIs Tipiracil. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: 2-Pyrimidinol, hydrochloride;, Pyrimidin-2-one monohydrochloride
CAS No: 38353-09-2
PubChem CID: 122774
Mol Formula: C4H5ClN2O
Mol Weight: 132.55 g/mol
Used in API: Tipiracil
IUPAC Name: 1H-pyrimidin-2-one;hydrochloride
API Intermediate Description: 2(1H)-Pyrimidinone, hydrochloride (1:1) is a key intermediate in the synthesis of the active pharmaceutical ingredient Tipiracil hydrochloride. In the synthetic pathway, 2(1H)-Pyrimidinone provides the pyrimidine core of Tipiracil. Through selective halogenation, substitution, and functional group transformations, it is elaborated into Tipiracil, which acts as a thymidine phosphorylase inhibitor. The hydrochloride salt form is used for stability and handling in synthesis.
