2-Methyl-1H-indole-3-ethylamine (CAS No: 2731-06-8) is a key pharmaceutical intermediate used in the synthesis of APIs Panobinostat. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: 2-Methyltryptamine, 2-methylindole-3-ethylamine
CAS No: 2731-06-8
PubChem CID: 75949
Mol Formula: C11H14N2
Mol Weight: 174.24 g/mol
Used in API: Panobinostat
IUPAC Name: 2-(2-methyl-1H-indol-3-yl)ethanamine
API Intermediate Description: 2-(2-Methyl-1H-indol-3-yl)ethanamine (also called 2-methyltryptamine) is a crucial building block for Panobinostat (LBH589) synthesis, acting as the indole core that is coupled with a cinnamic acid derivative, often via reductive amination, to form the final histone deacetylase (HDAC) inhibitor structure for cancer treatment. This key intermediate introduces the essential indole moiety, which is vital for the drug's biological activity, making its efficient synthesis a focus for industrial production.
