2-((1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl)-2,4-dihydro-4-(4-(4-(4-hydroxyphenyl)-1-piperazinyl)phenyl)-3H-1,2,4-triazol-3-one (CAS No: 184177-83-1) is a key pharmaceutical intermediate used in the synthesis of APIs Posaconazole. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: Anticancer agent 265, Posaconazole Impurity 4
CAS No: 184177-83-1
PubChem CID: 46223297
Mol Formula: C30H35N5O3
Mol Weight: 513.6 g/mol
Used in API: Posaconazole
IUPAC Name: 4-[4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl]-2-[(2S,3S)-2-phenylmethoxypentan-3-yl]-1,2,4-triazol-3-one
API Intermediate Description: 2-((1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl)-2,4-dihydro-4-(4-(4-(4-hydroxyphenyl)-1-piperazinyl)phenyl)-3H-1,2,4-triazol-3-one is a white solid pharmaceutical intermediate plays a key role in the synthesis of posaconazole, an antifungal drug. This compound has a melting point of 195-197°C, slight solubility in chloroform and methanol, and is stored under inert gas at 2-8°C.
