1-((2-Fluorophenyl)methyl)-1H-pyrazolo(3,4-b)pyridine-3-carboximidamide hydrochloride (CAS No: 1630906-65-8) is a key pharmaceutical intermediate used in the synthesis of APIs Riociguat. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: 1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide hydrochloride,1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide hydrochloride
CAS No: 1630906-65-8
PubChem CID: 57415844
Mol Formula: C14H13ClFN5
Mol Weight: 305.74 g/mol
Used in API: Riociguat
IUPAC Name: 1-[(2-fluorophenyl)methyl]pyrazolo[5,4-b]pyridine-3-carboximidamide;hydrochloride
API Intermediate Description: 1-((2-Fluorophenyl)methyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide hydrochloride is a heterocyclic amidine salt used as a synthetic and research intermediate in medicinal chemistry.It consists of a pyrazolo[3,4-b]pyridine fused heterocyclic core substituted at the N-1 position with a 2-fluorobenzyl group, and bearing a carboximidamide (amidine) functionality at the 3-position. The hydrochloride salt form enhances chemical stability, solubility, and handling of the strongly basic amidine group.
